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Eigen Bio Reports Top-Three Result in Stanford RNA 3D Challenge

Eigen Bio announced a top-three finish in the 2025 Stanford RNA 3D Folding Challenge and described its approach to RNA structure prediction.

New York, New York
Colorful RNA structure illustration accompanying Eigen Bio's announcement

Announcement

Eigen Bio announced on September 29, 2025 that its team finished among the top three in the Stanford RNA 3D Folding Challenge. Stanford's Das Lab separately congratulated team Eigen among the leading competitors in the blind prediction challenge.

The competition asked participants to predict the three-dimensional structures of RNA molecules from sequence data. Eigen Bio presented the result as an important milestone for its machine-learning work and reported that the challenge drew participants from many countries and thousands of submissions.

The company's announcement compared its performance with Google DeepMind's AlphaFold3. That comparison was a company claim about a particular challenge and metric; it should not be read as proof that one system is generally superior across all RNA or biological-structure tasks.

Eigen Bio also outlined ambitions in diagnostics, drug discovery, and therapeutic development. These were research and business goals at the time, not evidence of an approved medical product. Stanford's challenge update is linked below for independent context on the competition result.

Source and further information

Stanford Das Lab's challenge update